The prognosis for uveal melanoma patients depends on many factors, including the patient’s age, where in the uvea the tumour grew, its size and thickness, and whether it has spread outside of the eye.
If tissue from the tumour has been removed from the eye, for example via biopsy or surgery, additional information can be gathered by looking at the tissue under the microscope.
Further tests can also be done on the tumour to see what its genetic make-up is. If monosomy 3 is detected that usually means the patient is at high risk of developing metastatic disease.
Prognosis is highly individual, and your ocular oncologist will be able to advise you whether you are a high risk patient or not. Your ocular oncologist will be able to tell you how they reached the conclusion they did, and what this means for your future follow up.
If you would like to read more about prognostic methods, please visit this site compiled by Dr Bertil Damato (former lead at the Liverpool Ocular Oncology Centre.)
The pathologists and clinicians should work together to estimate your overall risk of developing metastatic disease. You should be offered the choice as to how much information you would like to know. The team at the eye centre should discuss the role of biopsy with you, including the benefits, risks and limitations of the procedure. You should consider the impact of any decision you make on your quality of life. – Lay Summary, Uveal Melanoma Guidelines